The Top 25 of ’25 eBook brings together the most influential research, technologies, and perspectives shaping next-generation biomed today.
Curated by the NextGen Biomed Academic Steering Group, this collection reflects a year of rapid scientific progress across biologics, immunotherapy, cell & gene therapy, oligonucleotides, peptides, and vaccines.
Developed for R&D leaders, innovators, and decision-makers, each featured article highlights practical progress, emerging best practice, and technologies moving from concept to application, supporting better decisions and stronger collaboration.
Benefits;
· Expert-led insight spanning proteins, antibodies & ADCs, cell & gene therapy, oligonucleotides, peptides, and small molecules
· Real-world examples of technologies improving scalability, efficiency, safety, and sustainability
· Perspectives from pharma, biotech, academia, and regulators shaping the future of biomedical innovation
· A curated resource designed to inform strategy, spark collaboration, and support long-term progress
Featured article: Sweep and Destroy – Engineering Antibodies for FcRn Engagement
Karen Silence, Vice President, argenx
One of the standout contributions in the eBook explores how antibody engineering can be used to actively remove pathogenic targets from circulation.
Karen Silence examines how FcRn biology can be leveraged to create sweeping antibodies that repeatedly bind, internalise, and degrade disease-driving molecules.
Drawing on the development of efgartigimod and next-generation one-armed antibody formats, the piece offers a compelling look at how antibody design is evolving to improve efficacy while addressing key clinical challenges.
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