As demand of peptide-based therapeutics continues to grow, there is increasing pressure on industry to improve process efficiency and ensure consistent product quality while reducing environmental impact and operational complexity. This presentation will discuss several innovation process developments in the context of peptide manufacturing, with a focus on research and development activities that aim to enable efficient and scalable production. The talk will address key stages of peptide production, including solid-phase peptide synthesis (SPPS), purification and isolation of the product, with particular emphasis on the design of environmental friendly and sustainable approaches that are compatible with future scale-up. Selected examples will be used to illustrate practical adjustment and optimisation of the process. Overall, the presentation aims to provide insight into how innovation in peptide manufacturing process can lay a strong foundation for future sustainable and efficient manufacturing.
Simin Chen, Peptide Researcher, Asymchem