•Over the last few years SCIEX have been developing new tools to enable Scientists to dig deeper and more quickly and accurately profile impurities in protein biotherapeutics. In this short talk you will discover how Native Fluorescence has been developed by SCIEX and how it is improving fragment and charge impurity detection in capillary electrophoresis providing a more sensitive detection than UV without the need for derivatisation
•When a deeper understanding of the impurities is required, LCMS is used and, in this presentation, you will learn how the ZenoTOF 8600 system is enhancing peptide mapping using both CID and electron-activated dissociation (EAD) to confidentiality characterise low level impurities. With its new ion transmission also discover how this system improves intact native analysis of large protein biotherapeutics
Stephen Lock, Senior Marketing and Market Development Manager, Sciex
